Download A Beginner's Guide to Blood Cells by Barbara J. Bain PDF

By Barbara J. Bain

This well known notebook has been updated and expanded all through, delivering a concise view of diagnostic haematology, in a handy and useful format.

A Beginner's advisor to Blood Cells is a perfect for;

  • Trainee laboratory technicians and scientists
  • Students learning the body structure or pathology of the blood
  • Those getting ready for haematology examinations

Why purchase This Book?

  • Unique pocket advisor, written by way of Barbara Bain – a world-renowned professional within the box of blood morphology
  • Outlines the fundamentals of diagnostic haematology
  • Includes a useful self-assessment section
  • NEW EDITION – now contains additional info on medical facets and additional tests
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Sample text

Assessing Red Cells 31 increase in high-molecular-weight plasma proteins there is an effect on the electrical charge on the surface of the red cells and the cells sediment rapidly and form into stacks, like a pile of coins. These stacks are referred to as rouleaux (Fig. 4) and the film is said to show increased rouleaux formation. The other abnormality of cell distribution is red cell agglutination. This is caused by an antibody against a red cell antigen. The antibodycoated red cells become sticky and form into irregularly shaped Fig.

This process is also known as crenation. 26 Chapter 1 Fig. 20 Storage artefact. The red cells are crenated, a lymphocyte (right) has a fuzzy outline and one of the two neutrophils (left) has a nucleus which has become round, dense and homogeneous. (Compare the degenerating neutrophil with the nucleated red cells shown in Fig. ) Some of the white cells develop fuzzy outlines or disintegrate entirely when the blood film is spread. The nuclei of neutrophils become dense, homogeneous and round and may break up into two or more round masses.

Characteristic morphological changes occur in lymphocytes in different types of leukaemia and lymphoma (see Chapter 4). Assessing morphology of monocytes, eosinophils and basophils Numerical changes in monocytes, eosinophils and basophils are often useful in diagnosis but this is less often the case with morphological changes. Monocytes can show increased size and cytoplasmic vacuolation during infection. Immature monocytes with increased gran- Fig. 11 Eosinophil leucocytosis with one of the three eosinophils being markedly hypogranular.

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