Hematology

Download Calcium signalling: Approaches and Findings in the Heart and by Lars Kaestner PDF

By Lars Kaestner

The booklet combines common thoughts and strategies to enquire calcium signalling in cells starting from molecular biology methods to manipulation of calcium in residing cells. the focal point inside those tools in at the large variety of fluorescence imaging know-how, specifically on optical sectioning thoughts and speedy photograph acquisition. as well as those normal instructions there are program examples in a context past calcium signalling in significant fields: investigations of remoted cardiac myocytes and crimson blood mobile comparable study. whereas the mobile cardiology part offers snapshots of sure calcium signalling features, the purple blood cellphone half provides an summary from the practical id of calcium-channels to an idea of physiological and pathophysiological relevance.

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73, 419–427 (2009). [104] Eder, P. & Molkentin, J. D. TRPC channels as effectors of cardiac hypertrophy. Circulation Research 108, 265–272 (2011). [105] Seeber, S. et al. Transient expression of NMDA receptor subunit NR2B in the developing rat heart. Journal of neurochemistry 75, 2472–2477 (2000). [106] Bers, D. M. Excitation-Contraction Coupling and Cardiac Contractile Force. (Kluwer Academic Publishers: Dordrecht, Boston, London, 2001). [107] Zipes, D. P. & Jalife, J. Cardiac Electrophysiology: From Cell to Bedside.

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A. et al. Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1. Journal of Clinical Investigation 105, 875–886 (2000). [93] Iribe, G. et al. Axial stretch of rat single ventricular cardiomyocytes causes an acute and transient increase in Ca2+ spark rate. Circulation Research 104, 787–795 (2009). [94] Antovic, J. P. & Blombäck, M. Essential Guide to Blood Coagulation. (Wiley-Blackwell: Oxford, 2010). , Neu, B. & Meiselman, H. J. Red blood Cell Aggregation.

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