Download Early vascular aging (EVA) : new directions in by Peter M Nilsson, Michael Hecht Olsen, Stephane Laurent PDF

By Peter M Nilsson, Michael Hecht Olsen, Stephane Laurent

Early Vascular getting older (EVA): New instructions in Cardiovascular safeguard brings jointly the decade of analysis on the topic of the characterization of EVA, in addition to the predictive strength of pulse wave pace (PWV).

The booklet offers a unique method of the matter of heart problems, exhibiting it with regards to nice vessels ailment and revealing a entire method of the matter of elevated pressure of the nice vessels, its explanations, and additional results.

Information supplied is observed by means of on-line entry to a supplemental web site with videos of anatomic specimens, cardiac imaging, and surgical procedures.

  • Introduces the most recent info on early vascular getting older (EVA), whole with summaries of contemporary facts and instructions for proper hazard issue control
  • Ideal reference for the research of vascular getting older, pulse wave speed, arteriosclerosis, EVA, arterial stiffness, vascular, PWV biomarkers, and cardiovascular disease
  • Contains the entire suitable info to be had from diverse fields of information (from simple biology to epidemiology) in regard to EVA
  • Provides proof that results in a brand new goal for interventions, early vascular getting older (EVA) in topics with early onset elevated arterial stiffness
  • Includes on-line entry to a supplemental site with videos of anatomic specimens, cardiac imaging, and surgical procedures

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Additional info for Early vascular aging (EVA) : new directions in cardiovascular protection

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46] Cunha PG, Cotter J, Oliveira P, Vila I, Boutouyrie P, Laurent S, et al. Pulse wave velocity distribution in a cohort study: from arterial stiffness to early vascular aging. J Hypertens 2015;33(7):1438À45. [47] Berglund G, Elmstahl S, Janzon L, Larsson SA. The Malmo Diet and Cancer Study. Design and feasibility. J Intern Med 1993;233:45À51. [48] Gottsater M, Ostling G, Persson M, Engstro¨m G, Melander O, Nilsson PM. Non-hemodynamic predictors of arterial stiffness after 17 years of follow-up: the Malmo Diet and Cancer study.

After the definition of the arterial phenotypes as described above, we set to examine the lifelong RF exposures that could explain why individuals of the same chronological age differ in arterial age by as much as two decades (T1 vs T3). EARLY DETERMINANTS OF ARTERIAL STIFFNESS—A LIFE COURSE APPROACH As the twig is bent, so is the tree inclined. Proverbial saying from the early 18th century2. The first arterial studies conducted within the AGAHLS reported that RFs other than elevated BP (a known major determinant), such as poorer cardiopulmonary fitness, a central pattern of fat distribution and the metabolic syndrome (MetS) were cross-sectionally associated with higher levels of arterial stiffness.

Surprisingly in this cohort other than blood pressure, established cardiovascular risk factors had only a modest effect on aortic stiffness and wave reflection, whilst inflammation emerged as in important predictor [50]. In a similar vein, in 3,769 men and women from the Whitehall II cohort, a wide range of traditional and novel cardiovascular risk factors were determined at baseline (1991À1993) and aortic PWV was measured at follow-up (2007À2009). In this large prospective study, central obesity (often closely associated with inflammation) was a strong predictor of aortic stiffness.

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